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Conditional Analysis of Multiple Quantitative Traits Based on Marginal GWAS Summary Statistics

There has been an increasing interest in joint association testing of multiple traits for possible pleiotropic effects. However, even in the presence of pleiotropy, most of the existing methods cannot distinguish direct and indirect effects of a genetic variant, say SNP, on multiple traits, and a co...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Deng, Yangqing, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536980/
https://ncbi.nlm.nih.gov/pubmed/28464407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22046
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