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Statistical Methods for Testing Genetic Pleiotropy

Genetic pleiotropy is when a single gene influences more than one trait. Detecting pleiotropy and understanding its causes can improve the biological understanding of a gene in multiple ways, yet current multivariate methods to evaluate pleiotropy test the null hypothesis that none of the traits are...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Schaid, Daniel J., Tong, Xingwei, Larrabee, Beth, Kennedy, Richard B., Poland, Gregory A., Sinnwell, Jason P.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068841/
https://ncbi.nlm.nih.gov/pubmed/27527515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.189308
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