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Multivariate generalized linear model for genetic pleiotropy

When a single gene influences more than one trait, known as pleiotropy, it is important to detect pleiotropy to improve the biological understanding of a gene. This can lead to improved screening, diagnosis, and treatment of diseases. Yet, most current multivariate methods to evaluate pleiotropy tes...

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Bibliografiske detaljer
Udgivet i:Biostatistics
Main Authors: Schaid, Daniel J, Tong, Xingwei, Batzler, Anthony, Sinnwell, Jason P, Qing, Jiang, Biernacka, Joanna M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296339/
https://ncbi.nlm.nih.gov/pubmed/29267957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxx067
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