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Testing Genetic Linkage with Relative Pairs and Covariates by Quasi-Likelihood Score Statistics

BACKGROUND/AIMS: Genetic linkage analysis of common diseases is complicated by the heterogeneity of genetic and environmental factors that increase disease risk, and possibly interactions among them. Most linkage methods that account for covariates are restricted to sib pairs, with the exception of...

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Autori principali: Schaid, Daniel J., Sinnwell, Jason P., Thibodeau, Stephen N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880728/
https://ncbi.nlm.nih.gov/pubmed/17565225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000103751
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