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Testing Genetic Linkage with Relative Pairs and Covariates by Quasi-Likelihood Score Statistics

BACKGROUND/AIMS: Genetic linkage analysis of common diseases is complicated by the heterogeneity of genetic and environmental factors that increase disease risk, and possibly interactions among them. Most linkage methods that account for covariates are restricted to sib pairs, with the exception of...

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Detalhes bibliográficos
Main Authors: Schaid, Daniel J., Sinnwell, Jason P., Thibodeau, Stephen N.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880728/
https://ncbi.nlm.nih.gov/pubmed/17565225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000103751
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