Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association

BACKGROUND: In this paper, we propose a one degree of freedom test for association between a candidate gene and a binary trait. This method is a generalization of Terwilliger's likelihood ratio statistic and is especially powerful for the situation of one associated haplotype. As an alternative...

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Библиографические подробности
Главные авторы: el Galta, Rachid, Uitte de Willige, Shirley, de Visser, Marieke CH, Helmer, Quinta, Hsu, Li, Houwing-Duistermaat, Jeanine J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231383/
https://ncbi.nlm.nih.gov/pubmed/17892585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-63
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