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Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association
BACKGROUND: In this paper, we propose a one degree of freedom test for association between a candidate gene and a binary trait. This method is a generalization of Terwilliger's likelihood ratio statistic and is especially powerful for the situation of one associated haplotype. As an alternative...
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Glavni autori: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2007
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2231383/ https://ncbi.nlm.nih.gov/pubmed/17892585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-63 |
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