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Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN‐amplified retinoblastoma
A small, but unique subgroup of retinoblastoma has been identified with no detectable mutation in the retinoblastoma gene (RB1) and with high levels of MYCN gene amplification. This manuscript investigated alternate pathways of inactivating pRb, the encoded protein in these tumors. We analyzed the m...
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| Veröffentlicht in: | Cancer Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345671/ https://ncbi.nlm.nih.gov/pubmed/28211617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1010 |
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