Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia

BACKGROUND: Improved diagnostics for typhoid are needed; a typhoid controlled human infection model may accelerate their development and translation. Here, we evaluated a blood culture-PCR assay for detecting infection after controlled human infection with S. Typhi and compared test performance with...

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Publié dans:J Infect
Auteurs principaux: Darton, Thomas C., Zhou, Liqing, Blohmke, Christoph J., Jones, Claire, Waddington, Claire S., Baker, Stephen, Pollard, Andrew J.
Format: Artigo
Langue:Inglês
Publié: W.B. Saunders 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345565/
https://ncbi.nlm.nih.gov/pubmed/28130144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2017.01.006
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