Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia

BACKGROUND: Improved diagnostics for typhoid are needed; a typhoid controlled human infection model may accelerate their development and translation. Here, we evaluated a blood culture-PCR assay for detecting infection after controlled human infection with S. Typhi and compared test performance with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Infect
Prif Awduron: Darton, Thomas C., Zhou, Liqing, Blohmke, Christoph J., Jones, Claire, Waddington, Claire S., Baker, Stephen, Pollard, Andrew J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: W.B. Saunders 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345565/
https://ncbi.nlm.nih.gov/pubmed/28130144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2017.01.006
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg