Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever

Enteric fever, caused by Salmonella enterica serovar Typhi, is an important public health problem in resource-limited settings and, despite decades of research, human responses to the infection are poorly understood. In 41 healthy adults experimentally infected with wild-type S. Typhi, we detected s...

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Gepubliceerd in:J Exp Med
Hoofdauteurs: Blohmke, Christoph J., Darton, Thomas C., Jones, Claire, Suarez, Nicolas M., Waddington, Claire S., Angus, Brian, Zhou, Liqing, Hill, Jennifer, Clare, Simon, Kane, Leanne, Mukhopadhyay, Subhankar, Schreiber, Fernanda, Duque-Correa, Maria A., Wright, James C., Roumeliotis, Theodoros I., Yu, Lu, Choudhary, Jyoti S., Mejias, Asuncion, Ramilo, Octavio, Shanyinde, Milensu, Sztein, Marcelo B., Kingsley, Robert A., Lockhart, Stephen, Levine, Myron M., Lynn, David J., Dougan, Gordon, Pollard, Andrew J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2016
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886356/
https://ncbi.nlm.nih.gov/pubmed/27217537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151025
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