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Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Fleury Curado, Thomaz, Fishbein, Kenneth, Pho, Huy, Brennick, Michael, Dergacheva, Olga, Sennes, Luiz U., Pham, Luu V., Ladenheim, Ellen E., Spencer, Richard, Mendelowitz, David, Schwartz, Alan R., Polotsky, Vsevolod Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345079/
https://ncbi.nlm.nih.gov/pubmed/28281681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44392
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