Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Fleury Curado, Thomaz, Fishbein, Kenneth, Pho, Huy, Brennick, Michael, Dergacheva, Olga, Sennes, Luiz U., Pham, Luu V., Ladenheim, Ellen E., Spencer, Richard, Mendelowitz, David, Schwartz, Alan R., Polotsky, Vsevolod Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345079/
https://ncbi.nlm.nih.gov/pubmed/28281681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44392
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