Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fleury Curado, Thomaz, Fishbein, Kenneth, Pho, Huy, Brennick, Michael, Dergacheva, Olga, Sennes, Luiz U., Pham, Luu V., Ladenheim, Ellen E., Spencer, Richard, Mendelowitz, David, Schwartz, Alan R., Polotsky, Vsevolod Y.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345079/
https://ncbi.nlm.nih.gov/pubmed/28281681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44392
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires