The Effect of DREADD Activation of Leptin Receptor Positive Neurons in the Nucleus of the Solitary Tract on Sleep Disordered Breathing

Obstructive sleep apnea (OSA) is recurrent obstruction of the upper airway due to the loss of upper airway muscle tone during sleep. OSA is highly prevalent, especially in obesity. There is no pharmacotherapy for OSA. Previous studies have demonstrated the role of leptin, an adipose-tissue-produced...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Amorim, Mateus R., Dergacheva, Olga, Fleury-Curado, Thomaz, Pho, Huy, Freire, Carla, Mendelowitz, David, Branco, Luiz G. S., Polotsky, Vsevolod Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269100/
https://ncbi.nlm.nih.gov/pubmed/34201760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136742
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