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The Effect of DREADD Activation of Leptin Receptor Positive Neurons in the Nucleus of the Solitary Tract on Sleep Disordered Breathing

Obstructive sleep apnea (OSA) is recurrent obstruction of the upper airway due to the loss of upper airway muscle tone during sleep. OSA is highly prevalent, especially in obesity. There is no pharmacotherapy for OSA. Previous studies have demonstrated the role of leptin, an adipose-tissue-produced...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Amorim, Mateus R., Dergacheva, Olga, Fleury-Curado, Thomaz, Pho, Huy, Freire, Carla, Mendelowitz, David, Branco, Luiz G. S., Polotsky, Vsevolod Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269100/
https://ncbi.nlm.nih.gov/pubmed/34201760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136742
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