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Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair
Apurinic/apyrimidinic (AP) sites are frequently generated in the genome by spontaneous depurination/depyrimidination or after removal of oxidized/modified bases by DNA glycosylases during the base excision repair (BER) pathway. Unrepaired AP sites are mutagenic and block DNA replication and transcri...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342734/ https://ncbi.nlm.nih.gov/pubmed/27655688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12113 |
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