PAK4 suppresses PDZ-RhoGEF activity to drive invadopodia maturation in melanoma cells

Cancer cells are thought to use actin rich invadopodia to facilitate matrix degradation. Formation and maturation of invadopodia requires the co-ordained activity of Rho-GTPases, however the molecular mechanisms that underlie the invadopodia lifecycle are not fully elucidated. Previous work has sugg...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Nicholas, Nicole S., Pipili, Aikaterini, Lesjak, Michaela S., Ameer, Simon M., Geh, Jenny L. C., Healy, Ciaran, Ross, Alistair D. MacKenzie, Parsons, Maddy, Nestle, Frank O., Lacy, Katie E., Wells, Claire M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342596/
https://ncbi.nlm.nih.gov/pubmed/27765920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12282
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars