MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4

Amplification of the MYCN oncogene, a member of the MYC family of transcriptional regulators, is one of the most powerful prognostic markers identified for poor outcome in neuroblastoma, the most common extracranial solid cancer in childhood. While MYCN has been established as a key driver of malign...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Xue, Chengyuan, Yu, Denise M.T., Gherardi, Samuele, Koach, Jessica, Milazzo, Giorgio, Gamble, Laura, Liu, Bing, Valli, Emanuele, Russell, Amanda J., London, Wendy B., Liu, Tao, Cheung, Belamy B., Marshall, Glenn M., Perini, Giovanni, Haber, Michelle, Norris, Murray D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342392/
https://ncbi.nlm.nih.gov/pubmed/27448979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10709
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