Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

Tumor profiling of DNA alterations, i.e. gene point mutations, somatic copy number aberrations (CNAs) and structural variants (SVs), improves insight into the molecular pathology of cancer and clinical outcome. Here, associations between genomic aberrations and disease recurrence in stage II and III...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: van den Broek, Evert, Krijgsman, Oscar, Sie, Daoud, Tijssen, Marianne, Mongera, Sandra, van de Wiel, Mark A., Th. Belt, Eric J., den Uil, Sjoerd H., Bril, Herman, Stockmann, Hein B.A.C., Ylstra, Bauke, Carvalho, Beatriz, Meijer, Gerrit A., Fijneman, Remond J.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342020/
https://ncbi.nlm.nih.gov/pubmed/27729614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12510
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