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MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer

BACKGROUND: Colorectal cancer (CRC) is caused by genetic aberrations. MACROD2 is commonly involved in somatic focal DNA copy number losses, in more than one-third of CRCs. In this study, we aimed to investigate the association of MACROD2 protein expression with clinical outcome in stage II and stage...

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Publicado en:Oncotarget
Main Authors: van den Broek, Evert, den Uil, Sjoerd H., Coupé, Veerle M.H., Delis-van Diemen, Pien M., Bolijn, Anne S., Bril, Herman, Stockmann, Hein B.A.C., van Grieken, Nicole C.T., Meijer, Gerrit A., Fijneman, Remond J.A.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047676/
https://ncbi.nlm.nih.gov/pubmed/30034629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25655
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