Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence

BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide. Accurately identifying stage II CRC patients at risk for recurrence is an unmet clinical need. KCNQ1 was previously identified as a tumour suppressor gene and loss of expression was associated with poor survival in patien...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: den Uil, Sjoerd H, Coupé, Veerle M H, Linnekamp, Janneke F, van den Broek, Evert, Goos, Jeroen A C M, Delis-van Diemen, Pien M, Belt, Eric J Th, van Grieken, Nicole C T, Scott, Patricia M, Vermeulen, Louis, Medema, Jan Paul, Bril, Herman, Stockmann, Hein B A C, Cormier, Robert T, Meijer, Gerrit A, Fijneman, Remond J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155368/
https://ncbi.nlm.nih.gov/pubmed/27855440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.376
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