Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

Tumor profiling of DNA alterations, i.e. gene point mutations, somatic copy number aberrations (CNAs) and structural variants (SVs), improves insight into the molecular pathology of cancer and clinical outcome. Here, associations between genomic aberrations and disease recurrence in stage II and III...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: van den Broek, Evert, Krijgsman, Oscar, Sie, Daoud, Tijssen, Marianne, Mongera, Sandra, van de Wiel, Mark A., Th. Belt, Eric J., den Uil, Sjoerd H., Bril, Herman, Stockmann, Hein B.A.C., Ylstra, Bauke, Carvalho, Beatriz, Meijer, Gerrit A., Fijneman, Remond J.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342020/
https://ncbi.nlm.nih.gov/pubmed/27729614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12510
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