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Mitophagy and Alzheimer’s disease: cellular and molecular mechanisms
Neurons affected in Alzheimer’s disease (AD) experience mitochondrial dysfunction and a bioenergetic deficit that occurs early and promotes the disease-defining amyloid β-peptide (Aβ) and Tau pathologies. Emerging findings suggest that the autophagy – lysosome pathway that removes damaged mitochondr...
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| Publicado no: | Trends Neurosci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341618/ https://ncbi.nlm.nih.gov/pubmed/28190529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2017.01.002 |
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