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Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease

Mitophagy is a selective engulfment and degradation of damaged mitochondria through the cellular autophagy machinery, a major mechanism responsible for mitochondrial quality control. Increased accumulation of damaged mitochondria in the Alzheimer’s disease (AD) human brain are evident, although unde...

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Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Xie, Chenglong, Aman, Yahyah, Adriaanse, Bryan A., Cader, M. Zameel, Plun-Favreau, Hélène, Xiao, Jian, Fang, Evandro F.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978796/
https://ncbi.nlm.nih.gov/pubmed/32010698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00391
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