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NAD(+) in Aging: Molecular Mechanisms and Translational Implications

The coenzyme NAD(+) is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of NAD(+) levels is important for cells with high energy demands and for proficien...

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Bibliographic Details
Published in:Trends Mol Med
Main Authors: Fang, Evandro F., Lautrup, Sofie, Hou, Yujun, Demarest, Tyler G., Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494058/
https://ncbi.nlm.nih.gov/pubmed/28899755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2017.08.001
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