NAD(+) supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

Senescence phenotypes and mitochondrial dysfunction are implicated in aging and in premature aging diseases, including ataxia telangiectasia (A‐T). Loss of mitochondrial function can drive age‐related decline in the brain, but little is known about whether improving mitochondrial homeostasis allevia...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Yang, Beimeng, Dan, Xiuli, Hou, Yujun, Lee, Jong‐Hyuk, Wechter, Noah, Krishnamurthy, Sudarshan, Kimura, Risako, Babbar, Mansi, Demarest, Tyler, McDevitt, Ross, Zhang, Shiliang, Zhang, Yongqing, Mattson, Mark P., Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045911/
https://ncbi.nlm.nih.gov/pubmed/33734555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13329
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