DNA damage invokes mitophagy through a pathway involving Spata18

Mitochondria are vital for cellular energy supply and intracellular signaling after stress. Here, we aimed to investigate how mitochondria respond to acute DNA damage with respect to mitophagy, which is an important mitochondrial quality control process. Our results show that mitophagy increases aft...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Dan, Xiuli, Babbar, Mansi, Moore, Anthony, Wechter, Noah, Tian, Jingyan, Mohanty, Joy G, Croteau, Deborah L, Bohr, Vilhelm A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337932/
https://ncbi.nlm.nih.gov/pubmed/32453416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa393
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