A carregar...
Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells
Ataxia with oculomotor apraxia type 1 (AOA1) is an early onset progressive spinocerebellar ataxia caused by mutation in aprataxin (APTX). APTX removes 5′-AMP groups from DNA, a product of abortive ligation during DNA repair and replication. APTX deficiency has been suggested to compromise mitochondr...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486572/ https://ncbi.nlm.nih.gov/pubmed/30986824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz083 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|