An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele

Natural killer (NK) cells are known to play a role in mediating innate immunity, in enhancing adaptive immune responses, and have been implicated in mediating anti-tumor responses via antibody-dependent cell-mediated cytotoxicity (ADCC) by reactivity of CD16 with the Fc region of human IgG1 antibodi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jochems, Caroline, Hodge, James W., Fantini, Massimo, Fujii, Rika, Maurice, Y. Morillon, Greiner, John W., Padget, Michelle R., Tritsch, Sarah R., Tsang, Kwong Yok, Campbell, Kerry S., Klingemann, Hans, Boissel, Laurent, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341330/
https://ncbi.nlm.nih.gov/pubmed/27861156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13411
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