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An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele
Natural killer (NK) cells are known to play a role in mediating innate immunity, in enhancing adaptive immune responses, and have been implicated in mediating anti-tumor responses via antibody-dependent cell-mediated cytotoxicity (ADCC) by reactivity of CD16 with the Fc region of human IgG1 antibodi...
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出版年: | Oncotarget |
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主要な著者: | , , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Impact Journals LLC
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341330/ https://ncbi.nlm.nih.gov/pubmed/27861156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13411 |
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