An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele

Natural killer (NK) cells are known to play a role in mediating innate immunity, in enhancing adaptive immune responses, and have been implicated in mediating anti-tumor responses via antibody-dependent cell-mediated cytotoxicity (ADCC) by reactivity of CD16 with the Fc region of human IgG1 antibodi...

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Vydáno v:Oncotarget
Hlavní autoři: Jochems, Caroline, Hodge, James W., Fantini, Massimo, Fujii, Rika, Maurice, Y. Morillon, Greiner, John W., Padget, Michelle R., Tritsch, Sarah R., Tsang, Kwong Yok, Campbell, Kerry S., Klingemann, Hans, Boissel, Laurent, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341330/
https://ncbi.nlm.nih.gov/pubmed/27861156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13411
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