Lung cancer is associated with decreased expression of perforin, granzyme B and interferon (IFN)-γ by infiltrating lung tissue T cells, natural killer (NK) T-like and NK cells

There is a limited understanding how of lung cancer cells evade cytotoxic attack. Previously, we have shown reduced production of the cytotoxic mediator granzyme B by CD8(+) T cells in lung cancer tissue. We hypothesized that lung cancer would be further associated with decreased production of granz...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Hodge, G, Barnawi, J, Jurisevic, C, Moffat, D, Holmes, M, Reynolds, P N, Jersmann, H, Hodge, S
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360197/
https://ncbi.nlm.nih.gov/pubmed/24894428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12392
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