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Lung cancer is associated with decreased expression of perforin, granzyme B and interferon (IFN)-γ by infiltrating lung tissue T cells, natural killer (NK) T-like and NK cells
There is a limited understanding how of lung cancer cells evade cytotoxic attack. Previously, we have shown reduced production of the cytotoxic mediator granzyme B by CD8(+) T cells in lung cancer tissue. We hypothesized that lung cancer would be further associated with decreased production of granz...
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Pubblicato in: | Clin Exp Immunol |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
BlackWell Publishing Ltd
2014
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360197/ https://ncbi.nlm.nih.gov/pubmed/24894428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12392 |
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