Dinutuximab Synergistically Enhances the Cytotoxicity of Natural Killer Cells to Retinoblastoma Through the Perforin-Granzyme B Pathway

PURPOSE: Conventional chemotherapy and enucleation usually fail to cure advanced retinoblastoma. We investigated the retinoblastoma immune microenvironment and the efficacy of the combination of dinutuximab and CD16-expressing NK-92MI (NK-92MI(hCD16-GFP)) cells on retinoblastoma cells in this study....

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Huixue, Yang, Jie, Pan, Hui, Tai, Mei Chee, Maher, Mohamed H, Jia, Renbing, Ge, Shengfang, Lu, Linna
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218403/
https://ncbi.nlm.nih.gov/pubmed/32440155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S228532
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