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Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria
BACKGROUND: Mucosal delivery of therapeutic protein drugs or vaccines is actively investigated, in order to improve bioavailability and avoid side effects associated with systemic administration. Orally administered bacteria, engineered to produce anti-inflammatory cytokines (IL-10, IL-1Ra), have sh...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534112/ https://ncbi.nlm.nih.gov/pubmed/15516267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-4-27 |
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