Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria

BACKGROUND: Mucosal delivery of therapeutic protein drugs or vaccines is actively investigated, in order to improve bioavailability and avoid side effects associated with systemic administration. Orally administered bacteria, engineered to produce anti-inflammatory cytokines (IL-10, IL-1Ra), have sh...

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Detaylı Bibliyografya
Asıl Yazarlar: Porzio, Stefano, Bossù, Paola, Ruggiero, Paolo, Boraschi, Diana, Tagliabue, Aldo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2004
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC534112/
https://ncbi.nlm.nih.gov/pubmed/15516267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-4-27
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