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Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria
BACKGROUND: Mucosal delivery of therapeutic protein drugs or vaccines is actively investigated, in order to improve bioavailability and avoid side effects associated with systemic administration. Orally administered bacteria, engineered to produce anti-inflammatory cytokines (IL-10, IL-1Ra), have sh...
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| Publicado no: | BMC Biotechnol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15516267/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6750-4-27 |
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