In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii

BACKGROUND: Interleukin-1 (IL-1) is a cytokine involved in the initiation and amplification of the defence response in infectious and inflammatory diseases. IL-1 receptor antagonist (IL-1ra) is an inactive member of the IL-1 family and represents one of the most potent mechanisms for controlling IL-...

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Main Authors: Ricci, Susanna, Macchia, Giovanni, Ruggiero, Paolo, Maggi, Tiziana, Bossù, Paola, Xu, Li, Medaglini, Donata, Tagliabue, Aldo, Hammarström, Lennart, Pozzi, Gianni, Boraschi, Diana
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2003
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC222906/
https://ncbi.nlm.nih.gov/pubmed/13129437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-3-15
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