Oral Delivery of IL27 Recombinant Bacteria Attenuates Immune Colitis in Mice

BACKGROUND & AIMS: Treatment of inflammatory bowel disease (IBD) would benefit from specific targeting of therapeutics to the intestine. We developed a strategy for localized delivery of the immunosuppressive cytokine IL27, which is actively synthesized in situ by the food-grade bacterium Lactoc...

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Main Authors: Hanson, Miranda L., Hixon, Julie A., Li, Wenqing, Felber, Barbara K., Anver, Miriam R., Stewart, C. Andrew, Janelsins, Brian M., Datta, Sandip K., Shen, Wei, McLean, Mairi H., Durum, Scott K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920828/
https://ncbi.nlm.nih.gov/pubmed/24120477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.09.060
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