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IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice

IL-22 has multiple activities ranging from tissue repair to inflammation. To characterize the pathogenicity and plasticity of cells that produce IL-22, a novel reporter mouse strain was generated. Homeostatic IL-22 reporter expression was observed in intestinal lymphoid cells identified as CD4 T cel...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Shen, Wei, Hixon, Julie A., McLean, Mairi H., Li, Wen Qing, Durum, Scott K.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717188/
https://ncbi.nlm.nih.gov/pubmed/26834739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00662
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