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Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration

RNA-guided genome surgery using CRISPR-Cas9 nucleases has shown promise for the treatment of diverse genetic diseases. Yet, the potential of such nucleases for therapeutic applications in nongenetic diseases is largely unexplored. Here, we focus on age-related macular degeneration (AMD), a leading c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genome Res
Päätekijät: Kim, Kyoungmi, Park, Sung Wook, Kim, Jin Hyoung, Lee, Seung Hwan, Kim, Daesik, Koo, Taeyoung, Kim, Kwang-eun, Kim, Jeong Hun, Kim, Jin-Soo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340969/
https://ncbi.nlm.nih.gov/pubmed/28209587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.219089.116
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