Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration

RNA-guided genome surgery using CRISPR-Cas9 nucleases has shown promise for the treatment of diverse genetic diseases. Yet, the potential of such nucleases for therapeutic applications in nongenetic diseases is largely unexplored. Here, we focus on age-related macular degeneration (AMD), a leading c...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Kim, Kyoungmi, Park, Sung Wook, Kim, Jin Hyoung, Lee, Seung Hwan, Kim, Daesik, Koo, Taeyoung, Kim, Kwang-eun, Kim, Jeong Hun, Kim, Jin-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340969/
https://ncbi.nlm.nih.gov/pubmed/28209587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.219089.116
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