In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

Several CRISPR-Cas9 orthologues have been used for genome editing. Here, we present the smallest Cas9 orthologue characterized to date, derived from Campylobacter jejuni (CjCas9), for efficient genome editing in vivo. After determining protospacer-adjacent motif (PAM) sequences and optimizing single...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kim, Eunji, Koo, Taeyoung, Park, Sung Wook, Kim, Daesik, Kim, Kyoungmi, Cho, Hee-Yeon, Song, Dong Woo, Lee, Kyu Jun, Jung, Min Hee, Kim, Seokjoong, Kim, Jin Hyoung, Kim, Jeong Hun, Kim, Jin-Soo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473640/
https://ncbi.nlm.nih.gov/pubmed/28220790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14500
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires