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OTX2 activity at distal regulatory elements shapes the chromatin landscape of Group 3 medulloblastoma

Medulloblastoma is the most frequent malignant pediatric brain tumor and is divided into at least four subgroups known as Wnt, SHH, Group 3 and Group 4. Here we characterized gene regulation mechanisms in the most aggressive subtype, Group 3 tumors, through genome-wide chromatin and expression profi...

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מידע ביבליוגרפי
הוצא לאור ב:	Cancer Discov
Main Authors:	Boulay, Gaylor, Awad, Mary E., Riggi, Nicolo, Archer, Tenley C., Iyer, Sowmya, Boonseng, Wannaporn E., Rossetti, Nikki E, Naigles, Beverly, Rengarajan, Shruthi, Volorio, Angela, Kim, James C., Mesirov, Jill P., Tamayo, Pablo, Pomeroy, Scott L., Aryee, Martin J., Rivera, Miguel N.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2017
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5340587/ https://ncbi.nlm.nih.gov/pubmed/28213356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0844
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OTX2 activity at distal regulatory elements shapes the chromatin landscape of Group 3 medulloblastoma

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