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Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain

Alterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer. Here, we show that the BRG1/BRM-associated factor (BAF) chromatin remodeling complex, which is mutated in over 20% of human tumors, interacts with EWSR1, a member of a family of proteins with prio...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell
Main Authors: Boulay, Gaylor, Sandoval, Gabriel J., Riggi, Nicolo, Iyer, Sowmya, Buisson, Rémi, Naigles, Beverly, Awad, Mary, E., Rengarajan, Shruthi, Volorio, Angela, McBride, Matthew J., Broye, Liliane C., Zou, Lee, Stamenkovic, Ivan, Kadoch, Cigall, Rivera, Miguel N.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791823/
https://ncbi.nlm.nih.gov/pubmed/28844694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.036
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