Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain

Alterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer. Here, we show that the BRG1/BRM-associated factor (BAF) chromatin remodeling complex, which is mutated in over 20% of human tumors, interacts with EWSR1, a member of a family of proteins with prio...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Boulay, Gaylor, Sandoval, Gabriel J., Riggi, Nicolo, Iyer, Sowmya, Buisson, Rémi, Naigles, Beverly, Awad, Mary, E., Rengarajan, Shruthi, Volorio, Angela, McBride, Matthew J., Broye, Liliane C., Zou, Lee, Stamenkovic, Ivan, Kadoch, Cigall, Rivera, Miguel N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791823/
https://ncbi.nlm.nih.gov/pubmed/28844694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.036
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