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Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain
Alterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer. Here, we show that the BRG1/BRM-associated factor (BAF) chromatin remodeling complex, which is mutated in over 20% of human tumors, interacts with EWSR1, a member of a family of proteins with prio...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6791823/ https://ncbi.nlm.nih.gov/pubmed/28844694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.036 |
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