Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain

Alterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer. Here, we show that the BRG1/BRM-associated factor (BAF) chromatin remodeling complex, which is mutated in over 20% of human tumors, interacts with EWSR1, a member of a family of proteins with prio...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Boulay, Gaylor, Sandoval, Gabriel J., Riggi, Nicolo, Iyer, Sowmya, Buisson, Rémi, Naigles, Beverly, Awad, Mary, E., Rengarajan, Shruthi, Volorio, Angela, McBride, Matthew J., Broye, Liliane C., Zou, Lee, Stamenkovic, Ivan, Kadoch, Cigall, Rivera, Miguel N.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791823/
https://ncbi.nlm.nih.gov/pubmed/28844694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.036
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires