Wheat germ agglutinin-conjugated liposomes incorporated with cardiolipin to improve neuronal survival in Alzheimer’s disease treatment

Curcumin (CRM) and nerve growth factor (NGF) were entrapped in liposomes (LIP) with surface wheat germ agglutinin (WGA) to downregulate the phosphorylation of kinases in Alzheimer’s disease (AD) therapy. Cardiolipin (CL)-conjugated LIP carrying CRM (CRM-CL/LIP) and also carrying NGF (NGF-CL/LIP) wer...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Kuo, Yung-Chih, Lin, Che-Yu, Li, Jay-Shake, Lou, Yung-I
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340244/
https://ncbi.nlm.nih.gov/pubmed/28280340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S128396
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