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Wheat germ agglutinin-conjugated liposomes incorporated with cardiolipin to improve neuronal survival in Alzheimer’s disease treatment

Curcumin (CRM) and nerve growth factor (NGF) were entrapped in liposomes (LIP) with surface wheat germ agglutinin (WGA) to downregulate the phosphorylation of kinases in Alzheimer’s disease (AD) therapy. Cardiolipin (CL)-conjugated LIP carrying CRM (CRM-CL/LIP) and also carrying NGF (NGF-CL/LIP) wer...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Kuo, Yung-Chih, Lin, Che-Yu, Li, Jay-Shake, Lou, Yung-I
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340244/
https://ncbi.nlm.nih.gov/pubmed/28280340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S128396
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