A Vascular Gene Trap Screen Defines RasGRP3 as an Angiogenesis-Regulated Gene Required for the Endothelial Response to Phorbol Esters

We identified Ras guanine-releasing protein 3 (RasGRP3) as a guanine exchange factor expressed in blood vessels via an embryonic stem (ES) cell-based gene trap screen to identify novel vascular genes. RasGRP3 is expressed in embryonic blood vessels, down-regulated in mature adult vessels, and reexpr...

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Publicado en:Mol Cell Biol
Autores principales: Roberts, David M., Anderson, Amanda L., Hidaka, Michihiro, Swetenburg, Raymond L., Patterson, Cam, Stanford, William L., Bautch, Victoria L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15572660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.24.10515-10528.2004
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