Regulation of RasGRP via a Phorbol Ester-Responsive C1 Domain
As part of a cDNA library screen for clones that induce transformation of NIH 3T3 fibroblasts, we have isolated a cDNA encoding the murine homolog of the guanine nucleotide exchange factor RasGRP. A point mutation predicted to prevent interaction with Ras abolished the ability of murine RasGRP (mRas...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.6995 |
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