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Regulation of RasGRP via a Phorbol Ester-Responsive C1 Domain

As part of a cDNA library screen for clones that induce transformation of NIH 3T3 fibroblasts, we have isolated a cDNA encoding the murine homolog of the guanine nucleotide exchange factor RasGRP. A point mutation predicted to prevent interaction with Ras abolished the ability of murine RasGRP (mRas...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Mol Cell Biol
Príomhchruthaitheoirí: Tognon, Cristina E., Kirk, Heather E., Passmore, Lori A., Whitehead, Ian P., Der, Channing J., Kay, Robert J.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Taylor & Francis 1998
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109282/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.6995
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