Regulation of RasGRP via a Phorbol Ester-Responsive C1 Domain

As part of a cDNA library screen for clones that induce transformation of NIH 3T3 fibroblasts, we have isolated a cDNA encoding the murine homolog of the guanine nucleotide exchange factor RasGRP. A point mutation predicted to prevent interaction with Ras abolished the ability of murine RasGRP (mRas...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Tognon, Cristina E., Kirk, Heather E., Passmore, Lori A., Whitehead, Ian P., Der, Channing J., Kay, Robert J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1998
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.6995
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