De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis

Sphingolipids are a diverse class of essential cellular lipids that function as structural membrane components and as signaling molecules. Cells acquire sphingolipids by both de novo biosynthesis and recycling of exogenous sphingolipids. The individual importance of these pathways for the generation...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Alexaki, Aikaterini, Clarke, Benjamin A., Gavrilova, Oksana, Ma, Yinyan, Zhu, Hongling, Ma, Xinran, Xu, Lingyan, Tuymetova, Galina, Larman, Bridget C., Allende, Maria L., Dunn, Teresa M., Proia, Richard L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339773/
https://ncbi.nlm.nih.gov/pubmed/28100772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756460
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