De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis

Sphingolipids are a diverse class of essential cellular lipids that function as structural membrane components and as signaling molecules. Cells acquire sphingolipids by both de novo biosynthesis and recycling of exogenous sphingolipids. The individual importance of these pathways for the generation...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Alexaki, Aikaterini, Clarke, Benjamin A., Gavrilova, Oksana, Ma, Yinyan, Zhu, Hongling, Ma, Xinran, Xu, Lingyan, Tuymetova, Galina, Larman, Bridget C., Allende, Maria L., Dunn, Teresa M., Proia, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339773/
https://ncbi.nlm.nih.gov/pubmed/28100772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756460
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