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Sphingosine-1-phosphate Phosphatase 1 Regulates Keratinocyte Differentiation and Epidermal Homeostasis

Sphingosine 1-phosphate (S1P) is a bioactive lipid whose levels are tightly regulated by its synthesis and degradation. Intracellularly, S1P is dephosphorylated by the actions of two S1P-specific phosphatases, sphingosine-1-phosphate phosphatases 1 and 2. To identify the physiological functions of S...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allende, Maria L., Sipe, Laura M., Tuymetova, Galina, Wilson-Henjum, Kelsey L., Chen, Weiping, Proia, Richard L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689979/
https://ncbi.nlm.nih.gov/pubmed/23637227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478420
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